International Chemical Safety Cards ASCORBIC ACID ICSC: 0379 Vitamin C L-Ascorbic acid L-Xyloascorbic acid 3-Oxo-L-gulofuranolactone (enol form) C6H8O6 Molecular mass: 176.12 ICSC #    0379 CAS #     50-81-7 RTECS # CI7650000 October 06, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Water spray, powder. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION Cough. Sore throat. Local exhaust or breathing protection. Fresh air, rest.  •SKIN Redness. Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Redness. Pain. Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Rinse mouth. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. Personal protection: P1 filter respirator for inert particles. Separated from strong oxidants, strong bases. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 0379 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards ASCORBIC ACID ICSC: 0379 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: ODOURLESS, WHITE TO SLIGHTLY YELLOW CRYSTALS OR POWDER PHYSICAL DANGERS: CHEMICAL DANGERS: The substance is a strong reducing agent and reacts with oxidants. The solution in water is a medium strong acid. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Melting point (decomposes): 190-192°C Density: 1.65 g/cm3 Solubility in water, g/100 ml: 33 Octanol/water partition coefficient as log Pow: -2.15 ENVIRONMENTAL DATA N O T E S ADDITIONAL INFORMATION ICSC: 0379 ASCORBIC ACID (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.