International Chemical Safety Cards ISOBUTYRIC ACID ICSC: 0903 2-Methylpropanoic acid Dimethylacetic acid Propionic acid, 2-methyl- C4H8O2 / (CH3)2CHCOOH Molecular mass: 88.11 ICSC #    0903 CAS #     79-31-2 RTECS # NQ4375000 UN #        2529 EC #         607-063-00-9 March 05, 2002 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Alcohol-resistant foam, powder, carbon dioxide. EXPLOSION Above 56°C explosive vapour/air mixtures may be formed. Above 56°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Burning sensation. Cough. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Skin burns. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Pain. Redness. Severe deep burns. Face shield. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Burning sensation. Shock or collapse. Do not eat, drink, or smoke during work. Give plenty of water to drink. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Remove all ignition sources. Collect leaking liquid in covered containers. Wash away spilled liquid with plenty of water. Fireproof. Separated from strong bases, food and feedstuffs . Do not transport with food and feedstuffs. Xn symbol R: 21/22 S: (2) UN Hazard Class: 3 UN Subsidiary Risks: 8 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0903 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards ISOBUTYRIC ACID ICSC: 0903 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The vapour is heavier than air. CHEMICAL DANGERS: The substance is a weak acid. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 152-155°C Melting point: -47°C Relative density (water = 1): 0.95 Solubility in water, g/100 ml at 20°C: 20 Vapour pressure, kPa at 14,7°C: 0.13 Relative vapour density (air = 1): 3.0 Flash point: 56°C c.c. Auto-ignition temperature: 481°C Explosive limits, vol% in air: 2-9 Octanol/water partition coefficient as log Pow: 0.88 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S NFPA Code: H1; F2; R0; Transport Emergency Card: TEC (R)-30GFC-III ADDITIONAL INFORMATION ICSC: 0903 ISOBUTYRIC ACID (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.