International Chemical Safety Cards PYRENE ICSC: 1474 Benzo (d,e,f) phenanthrene beta-Pyrene C16H10 Molecular mass: 202.26 ICSC #    1474 CAS #     129-00-0 RTECS # UR2450000 November 27, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Water spray, carbon dioxide, dry powder, alcohol-resistant foam, or polymer foam. EXPLOSION EXPOSURE  •INHALATION Avoid inhalation of dust . Fresh air, rest.  •SKIN Redness. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder . Do NOT let this chemical enter the environment. (Extra personal protection: P2 filter respirator for harmful particles.) Separated from strong oxidants. Keep in a well-ventilated room. Do not transport with food and feedstuffs. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1474 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards PYRENE ICSC: 1474 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: PALE YELLOW OR COLOURLESS SOLID IN VARIOUS FORMS PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing irritating fumes . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation , through the skin and by ingestion . INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: Exposure to sun may provoke an irritating effect of pyrene on skin and lead to chronic skin discoloration. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 404°C Melting point: 151°C Density: 1.27 g/cm3 Solubility in water: 0.135 mg/l at 25°C Vapour pressure, Pa at °C: 0.08 Octanol/water partition coefficient as log Pow: 4.88 ENVIRONMENTAL DATA Bioaccumulation of this chemical may occur in crustacea,in fish,in milk,in algae andin molluscs. It is strongly advised that this substance does not enter the environment. N O T E S Pyrene is one of many polycyclic aromatic hydrocarbons - standards are usually established for them as mixtures, e.g., coal tar pitch volatiles. However, pyrene may be encountered as a laboratory chemical in its pure form. Health effects of exposure to the substance have not been investigated adequately. See ICSC 1415 Coal-tar pitch. ADDITIONAL INFORMATION ICSC: 1474 PYRENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.